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A novel and optimized synthetic route has been developed for the preparation of diverse [1-(tert-Butoxycarbonyl)amino]propanol derivatives. This method utilizes a multi-step process involving the modification of readily available starting precursors. The pivotal step in this procedure is the establishment of the tert-Butoxycarbonyl group through a

Pregabalin, a widely prescribed drug for pain, has spurred significant interest in the development of analogs with potentially enhanced pharmacological properties. One notable strategy involves incorporating a 1-beta-carboxylic acid oxide (1-BCO) moiety into the pregabalin scaffold, aiming to influence its pharmacodynamics. This article delves into